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Chunk #21 — Model — Gene Frequency Distributions

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Data and theory point to mainly additive genetic variance for complex traits.
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Genetic variance components are obtained by integration of expressions for the variance as a function of p for a specific model of the gene frequency distribution. For multiple locus models the distribution of all loci is assumed to be identical and there is no linkage disequilibrium. We focus on the contribution of additive genetic variance (V A) to genotypic variance (V G).