Of further interest, the between-group PPI identified differences in connectivity with regions that map onto multiple functional networks. Neuroimaging has mapped large-scale networks as distinct functional systems including the DMN, attention/control, visual, auditory/phonology, motor and self-referential networks (Cordes et al., 2002; Damoiseaux et al., 2006; De Luca et al., 2006; Deco and Corbetta, 2011; Dosenbach et al., 2007; Fox et al., 2006; Hampson et al., 2006), which closely represent underlying anatomical connectivity (Deco and Corbetta, 2011). The FH+ subjects in our study had increased striatal couplings with attention and motor structures, specifically the medial SSMA, precuneus and pre-and postcentral gyri, while the FH− subjects decoupled these regions during incentive anticipation, representing distinctly different network utilization.
