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Chunk #17 — Results — Prospective association of tobacco smoking in 1975 on suicide risk to 2011, excluding those with co-morbid psychiatric and medical conditions

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Prospective association between tobacco smoking and death by suicide: a competing risks hazard analysis in a large twin cohort with 35-year follow-up.
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The risk of suicide to 2011 remained elevated among active smokers in 1975 relative to never smokers when those who qualified for state reimbursable antipsychotic medication (1964–2004) or psychiatric disability pension (1975–2004), or both, 34 of 232 suicides (14.6%), were excluded from the cohort (HR 2.77, 95% CI 1.93–3.99) (n = 198 suicides). When those who reported excess alcohol use in 1975 (⩾42 g/day for men and ⩾28 g/day for women) were removed, 4% of the sample, n = 800 (7%) men and n = 187 (2%) women, the risk of suicide remained elevated among active smokers to 2011 (HR 2.56, 95% CI 1.62–4.04). The risk of suicide also remained elevated among active smokers (HR 2.30, 95% CI 1.43–3.68) after excluding those broadly defined as ill, aged over 60 years, or at high risk of somatic disease prior to 1983 (Kujala et al. 2002) (n = 123 suicides) (Table 3). Excluding those with incident malignancy to 2011 according to the Finnish Cancer Registry (n = 4500, with 2739 deaths, 15 suicides), the risk of suicide among smokers remained elevated in