In total, we found over 68,300 nonsynonymous SNPs, 34,161 of which were novel (Table 2). In an early analysis, 21,657 nonsynonymous SNPs were validated as polymorphic in 620 samples using a custom genotyping array (Table 2; Supplementary Information). The mean minor allele frequency in the array data was 2.2% for 4,573 novel variants, and 26.2% for previously discovered variants.
