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Chunk #18 — Methods — Time-frequency measures

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Theta event-related synchronization is a biomarker for a morbid effect of alcoholism on the brain that may partially resolve with extended abstinence.
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To examine resting theta power, the resting EEG data were first corrected for ocular artifacts, then divided into 1024-msec half-overlapping epochs (i.e., the first 512 msec of each epoch overlapped with the last 512 msec of the preceding epoch). Epochs with EOG amplitude >75 μV were eliminated from further processing. Fourier transform-based spectral estimation, using Welch's periodogram method, was then applied to each artifact-free epoch using a Hamming window, resulting in power spectra with 1-Hz resolution. The mean absolute power within the same theta-frequency range used in the evoked and induced TF analyses (3–6 Hz, see below) was then calculated for each electrode site. Because the distribution of theta power was skewed, the data were log transformed.