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Chunk #28 — Results — Simulation

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Principal Component Analysis Reduces Collider Bias in Polygenic Score Effect Size Estimation.
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26% - 50%, (3) 51% - 75%, and (4) 76% - 99%. When rGE = 0.1 and confounder correlations range between 0.05-0.1 the model A3 PRS effect increases by 5%, 14%, 25%, and 37% for bins 1 through 4, respectively. When rGE = 0.5 and confounder correlations range between 0.05-0.1 the model PRS A3 effect increases by 25%, 75%, 146%, and 220% for bins 1 through 4.