After exclusion of the locus near HHIP and the five reported regions, meta-analysis test statistics still showed an excess of extreme values compared with expected values under the null, particularly for FEV1. Although we cannot rule out the possibility of residual population stratification, this indicates the potential to detect further loci associated with lung function (Supplementary Fig. 1a,b). We have provided a list of the top 2000 associations for FEV1 and for FEV1/FVC (Supplementary Table 5) as a resource to other investigators.
