Chunk #49 — Methods — Simulations

Source

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations.

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yes

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PLINK1.90 (note version 20 Mar was used in this study)52 was used to run GWAS for the simulated phenotypes in Population 1 using the simple linear association testing on HapMap3 SNPs. To mimic the imperfect LD between the causal variants and the SNP markers used in GWAS, the causal variants were always left out of the analysis.