but found no significant difference in the hazard of transitioning to dependence between Whites and Hispanics. Our study examines race/ethnicity differences in transition from use to dependence in a general population sample and builds on the existing literature by examining these differences, stratifying race/ethnicity groups by sex. While our results for Blacks are consistent with the Lopez-Quintero study, our findings for Hispanics differ. These differences may be explained by differences in sampling strategy, including the restriction of their sample to persons who participated in both Waves 1 and 2 and the restriction of our sample to Wave 1 participants younger than 45 years of age. Additionally, our studies used different covariates in the adjusted models.