Chunk #21 — Results — Genetic association and heterogeneity analyses

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In search of causal variants: refining disease association signals using cross-population contrasts.

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Ten of the 21 SNPs in the HapMap CEU-determined r2 ≥ 0.8 bin for rs16969968 were genotyped in our sample. In addition, we examined additional SNPs across chromosome 15 that were genotyped in our sample and found no additional SNPs having r2 ≥ 0.8 with rs16969968 in our own data. Table 1 shows HapMap CEU and YRI allele frequencies for all 21 SNPs in the bin, and also EA and AA allele frequencies in our sample for the 10 genotyped SNPs.