To discuss in depth mRNA sequence and function, the secondary structure for KCNJ6 mRNA was predicted using Mfold web server (v. 3.2) with default settings [25]. The KCNJ6 mRNA position 982–1082 was used to predict the local structure of the mRNA based on the nucleotide sequences of the GenBank database (accession number: NM_002240.2).