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Chunk #0 — INTRODUCTION

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Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis.
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Cocaine use is common in the United States. The National Survey on Drug Use and Health reported that in 2010 an estimated 0.6% of Americans aged 12 or older (i.e., one million people) used cocaine within the prior month (Substance Abuse and Mental Health Services Administration, 2011]. Cocaine dependence (CD) is associated with serious social, legal, medical, and psychiatric problems and thus represents a major public health problem in the United States.