Chunk #8 — Methods — Statistical methods

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

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Analysis of the replication case-control studies was carried out in a similar manner, by 1 df comparisons of allele frequencies with Danish and UK studies treated as separate strata. The family study was analyzed by the transmission/disequilibrium test (TDT).