evidence for a possible functional role of the rs1344706 SNP, thus suggesting that this variant may be the cis-regulatory element directly responsible for ZNF804A allelic expression imbalance. Our results fit reasonably well with the previously published study showing rs1344706 as a functional polymorphism, with potential effects on ZNF804A expression through altered DNA-protein interactions (Hill and Bray, 2011), and are also consistent with the previously reported association between the rs1344706 risk allele and higher total ZNF804A expression in the adult DLPFC (Riley et al., 2010).
