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Chunk #28 — Discussion

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Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes.
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Table 1). This may be due in part to the larger number of participants of EA included in the discovery GWAS datasets. Large genome-wide studies have historically focused on participants of EA, leading to an important gap in knowledge regarding genetic epidemiology across diverse ancestral groups that our field must address. Future research would benefit from using estimates for similarly sized samples on comparable phenotypes to determine if findings differ due to differences in sample sizes or differences in the phenotypes being examined.