the supramarginal gyrus, the angular gyrus, the precuneus, the paracentral lobule, and the posterior cingulate gyrus. The corpus striatum region consists of the caudate nucleus, the putamen, and the pallidum. Each higher level anatomical region consists of regions from both the hemispheres. Differences in mean correlation coefficients for 4005 pairs were aggregated into 32 pairs and the resulting differences were then normalized. (see also [52]). In the aggregation step, the number of decreased (−1) or increased connectivities (+1) for each of the 32 pairs ( = (8×8)/2) was counted. For example, to identify differential connectivity between the prefrontal lobe region and the occipital lobe region the number of decreased or increased connectivities between all pairs of sub-regions belonging to the prefrontal lobe region and occipital lobe region was counted. Since each brain region has a different number of sub-regions, the aggregated differential connectivity count was normalized by the number of possible connections between pairs of sub regions belonging to the two brain regions under investigation.
