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Chunk #44 — 3. RXRs, Ethanol Metabolism, and Alcoholic Liver Disease

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Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease.
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GSTs are encoded by at least 9 gene family: eight of them encode for cytosolic enzymes (namely, alpha, mu, theta, pi, zeta, sigma, kappa and chi—also called omega) whereas a ninth family, composed at least by six genes encode for microsomal enzymes [110]. GST enzymes of alpha, mu, and pi families account for the majority of cytosolic GST activity.