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Chunk #82 — Online Methods — Variant Calling

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Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
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Integrated snATAC-seq data were split into single bam files for each of the 143 individuals using sinto (https://timoast.github.io/sinto/). Duplicated bam files for the same sample were merged together with samtools.103 For variant calling, the Sentieon germline variant calling pipeline104 was used, namely: