(A). mRNA modules significantly correlated with AD case-status. Each point represents an individual transcript within each module, which are plotted by the absolute value of their expression correlation to AD case-status (Gene Significance) on the y-axis and module eigengene (Module Membership) on the x-axis. The regression line, correlation value and p-value is shown for each plot, which indicates that GS of transcripts increases with increasing intramodular connectivity (MM). (B). miRNA modules significantly correlated with AD case-status. Each point represents an individual miRNA transcript within each module, which are plotted by the absolute value of their expression correlation to AD case-status (Gene Significance) on the y-axis and module eigengene (Module Membership) on the x-axis. Similarly to mRNA modules, GS of miRNA transcripts increases with increasing intramodular connectivity (MM).