Chunk #37 — Materials and Methods — Resequencing of nAChR Genes, SNP Selection, and Genotyping

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A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.

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surveyed with a Phrap quality score of >30 are: CHRNA2 [Chr. 8] 27374096::27375538, 27376211::27377643, 27380318::27381167, 27382561::27383658, 27384018::27384835, 27392219::27392738 nts.; CHRNA5-CHRNA3-CHRNB4 [Chr. 15] 76644811::76645440, 76651089::76651811, 76659985::76660542, 76665576::76666420, 76667214::76668294, 76668898::76670309, 76672128::76676199, 76680573::76681761, 76696115::76696969, 76697824::76698624, 76700082::76700676, 76703348::76704858, 76708170::76709554, 76710234::76710990, 76713688::76715398, 76720101::76721040 nts.; CHRNA4 [Chr. 20] 61446755::61447910, 61448032::61448901, 61451297::61452331, 61457596::61458129, 61457956::61458391, 61461159::61461713 nts.; CHRNB3-CHRNA6 [Chr. 8] 42671565::42672135, 42682775::42683415, 42684268::42684976, 42704488::42705250, 42705850::42706962, 42710633::42711239, 42721158::42721408, 42726921::42727704, 42730060::42731305, 42730845::42731665, 42733016::42733750, 42739105::42739734, 42742436::42743042 nts.; CHRNA9 [Chr. 4] 40177941::40178826, 40178370::40179265, 40179840::40180696, 40191528::40192719, 40192719::40198282 nts.; CHRNA10 [Chr. 11] 3643245::3644701, 3644675::3645949, 3647081::3647752, 3647274::3648079, 3648702::3649607 nts.; CHRNB2 [Chr. 1] 151353228::151353745, 151354953::151356224, 151356569::151357823, 151361153::151362332 nts.