between the minimum value, taken over the entire age range, and the value at age 25. The statistical characteristics of the null hypothesis were determined by cumulative summation of each of 1000 permutations of the realized increments to provide 1000 randomized sequences of correlations, determining the difference between the minimum value and the value at age 25 for each randomized sequence, and then finding the mean and standard deviation of the 1000 resulting differences. The realized difference was then represented in terms of its distance in standard deviations from the mean as determined by the randomization process, and its significance estimated accordingly.
