We combined 18 population-based European studies with birth weight and GWA data available (total n = 26,836 individuals): two sub-samples from the 1958 British Birth Cohort (B58C-WTCCC, n = 2,195; B58C-T1DGC, n = 2,037); the Avon Longitudinal Study of Parents And Children (ALSPAC (Discovery); n = 1,418); the Children’s Hospital of Philadelphia (CHOP , n = 7,380); the COpenhagen Prospective Study on Asthma in Childhood (COPSAC-2000, n = 353); the European Prospective Investigation of Cancer (EPIC, n = 1,478); the Erasmus Rucphen Family (ERF) study (n = 325); two sub-samples from the Generation R study (Generation R (Discovery 1), n = 1,194; Generation R (Discovery 2), n = 1,410); the Helsinki Birth Cohort Study (HBCS, n = 1,566); the Lifestyle – Immune System – Allergy (LISA) study (n = 387); the Northern Finland 1966 Birth Cohort (NFBC1966; n = 4,333); two sub-samples of singleton births from the Netherlands Twin Register (NTR1, n = 414; NTR2, n = 247); the Orkney Complex Disease Study (ORCADES, n = 328); the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) study (n = 368); the Raine study (RAINE, n = 1,105); and the Sorbs study (SORBS, n = 298).