This cohort profile describes recruitment and the first 18 years of follow-up of the ‘Children of the 90s’, i.e. the children of the mothers eligible for recruitment during 1990–92. Recruitment and follow-up of the mothers is described in a companion article.4 Participants are now in early adulthood; however, the intention is for follow-up to be lifelong. The transgenerational and family-based nature of ALSPAC is being consolidated through the ALSPAC ‘Focus on Mothers’ mothers study, the ‘Focus on Fathers’ fathers study and follow-up of the next ALSPAC generation (ALSPAC-G2 study) through ‘COCO90s’ (Children of Children of the 90s). These initiatives are not described further here.
