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Chunk #23 — 4. Discussion

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White matter integrity in adolescents with histories of marijuana use and binge drinking.
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Interestingly, we observed increasing FA values with more marijuana use in white matter fiber tracts such as the left superior longitudinal fasciculus and the left superior corona radiata. In the superior longitudinal fasciculus, FA values and marijuana use episodes in the past three months were positively related. Also in this region, we found an unexpected positive relationship between lifetime drinking occasions and FA values, even though marijuana use and lifetime drinking frequency were not correlated.