Chunk #47 — MATERIALS AND METHODS — QC and association testing — Quality control

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Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.

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All individuals of both GWAS samples underwent SNP marker QC as described previously (4,45). In detail, QC filters for individuals were checked for Mendelian inconsistencies in the family-based GWAS sample (>5% of all SNPs), the application of an SNP call rate of 95% and a minimum genotyping quality as assessed by Affymetrix Contrast QC > 0.4.