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Chunk #35 — DISCUSSION — Investigation of AUD-Associated DNA Methylomic Alterations in Reward-Related Brain Region

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Review: DNA methylation and alcohol use disorders: Progress and challenges.
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brain epigenetic studies have generated interesting findings, they are limited by the small sizes of brain tissue samples and the unavailability of tissues from multiple reward-related brain regions. These limitations will be overcome with the increased access of a larger number of human brain tissues from human brain banks, such as the New South Wales Tissue Resource Centre (NSW-TRC) at the University of Sydney (Australia)98 that collects postmortem brain tissues from schizophrenia or AUD patients and matched healthy control subjects.