transcriptional response to ethanol, while changes observed in PFC and NAc were of comparable magnitude (Figure 1a). The transcriptional response to ethanol within each brain region included both unique and shared gene components. Roughly 1/3 of significantly ethanol-responsive genes in the PFC and NAc were unique to their respective regions, while greater than 50% of the VMB ethanol profile was specific to that region (Figure 1b).
