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Chunk #55 — Methods — PGC

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Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
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Lifetime DSM-IV diagnosis of AD in both EUR and AFR ancestries were analyzed by PGC, with details reported previously8. This included 5,638 individuals from Australia. To avoid overlap with the new QIMR Berghofer cohorts, we re-analyzed the PGC data without two Australian cohorts: Australian Alcohol and Nicotine Studies and Brisbane Longitudinal Twin Study. This yielded 9,938 cases and 30,992 controls of EUR ancestry and 3,335 cases and 2,945 controls of AFR ancestry.