Allele and genotype prevalences for the SNPs for the entire sample and the subset of ever-drinkers (N=1,129) are shown in Table 1. All SNP distributions were consistent with Hardy-Weinberg equilibrium expectations (Table 1). ADH1B-rs1229984 and ADH1B-rs1229982 were in strong LD (r2=0.67, D′=0.75), ADH1B-rs1229984 and ADH1C-rs698 showed moderate LD (r2=0.32, D′=0.44), and other marker combinations showed weaker LD (Table 2). Prevalence for the rs698-rs1229984 diplotype variable was as follows: low risk, 47.0%; intermediate risk, 47.1%; high risk, 6.0%.
