Figure 3 and Table S3 summarize the associations between genotyped and imputed SNPs and CPD in PLCO and NHS smokers for the chr15q25.1 region spanning CHRNA3 and CHRNA5. The strongest association signal we observe in this region is at rs2036527 (combined P = 8×10−5), located 10,051 base pairs 3′ of PSMA4 and 6,290 base pairs 5′ of CHRNA5 in a region of strong linkage diseqilibrium spanning both genes.
