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Chunk #20 — Results — Single variant (GWAS and meta-analyses), gene and pathway analyses

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Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
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We also conducted meta-analyses of our data with the two SNPs reported as genome-wide significant by the Army STARRS consortium.35 STARRS reported one locus for AA (rs159572) and one for EA (rs11085374).35 Results after meta-analysis for the reported SNPs were not genome-wide significant (rs159572, P=0.2744; rs11085374, P=1.74 × 10−05), perhaps unsurprisingly given lack of consistent association within the Army STARRS report itself.35