Because the families and individuals selected for genotyping as part of GAW14 were a subset of families from both the initial and replication datasets used for COGA's published analyses, we do not expect that results will be identical to those previously published. This Genetic Analysis Workshop provides a remarkable opportunity to compare genome surveys using microsatellites to those using SNPs, in a very rich dataset that has both qualitative (e.g., diagnosis) and quantitative (e.g., electrophysiological) phenotypes reflecting a common, complex disease, alcoholism. We hope that the data we have provided will serve as a stimulus for progress in the genetic analysis of complex diseases.