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Chunk #2 — Method — Phenotypic Measures

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Three mutually informative ways to understand the genetic relationships among behavioral disinhibition, alcohol use, drug use, nicotine use/dependence, and their co-occurrence: twin biometry, GCTA, and genome-wide scoring.
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to drinking, and compulsive drinking (e.g., little time for anything but drinking). Drug Use (DRG) included the number of lifetime marijuana uses, a count of the number of classes of illicit drugs a person had ever tried (e.g., stimulants, hallucinogens, PCP, etc.), and DSM-III-R symptoms of abuse and dependence for the drug to which a person reported the most symptoms. Finally, Behavioral Disinhibition (BD) included DSM-III-R symptoms of conduct disorder, adult antisocial behavior (the adult criteria for antisocial personality disorder), and other measures of antisocial and non-normative behavior (e.g., precocious sexual intercourse) and disinhibited personality traits (e.g., impulsivity, aggression).