After expression QC, the U219 gene expression set consisted of 2,752 NTR subjects. An additional 1,895 NESDA subjects (representing the NESDA baseline set) were used for replication in this report. Expression QC for NESDA followed the same steps as for NTR (except zygosity did not apply). The expression distributions of monozygotic and dizygotic twins were compared for differing mean expression (t-test) and differing variances (F-test for normally distribute data), performed separately within twin sets 1 and 2. No transcript showed significantly different mean expression between monozygotic and dizygotic twins, but four transcripts showed significantly (FDR q<0.05) different variances. However, of these four transcripts, none showed h2 q<0.05.
