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Chunk #12 — Methods — Measures — Twin Cohort — Outcomes: Substance Use and Dependence Symptoms

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Association of Obsessive-Compulsive Disorder and Obsessive-Compulsive Symptoms With Substance Misuse in 2 Longitudinal Cohorts in Sweden.
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Alcohol use problems were measured with the self-reported Alcohol Use Disorders Identification Test40 at 18 and 24 years of age. The Alcohol Use Disorders Identification Test is a 10-item scale; items 1 to 3 relate to consumption of alcohol (frequency and quantity) and items 4 to 10 measure alcohol dependence and harmful use (ie, loss of control, withdrawal, neglect of other pursuits, continued use despite harm). Previous research supports a 2-factor structure, where items 1 to 3 load on factor 1 and items 4 to 10 load on factor 2.41 We identified individuals who used alcohol based on item 1 of the Alcohol Use Disorders Identification Test. The outcome variable, alcohol dependence symptoms, was measured as the sum of items 4 to 10. Internal consistency of the scale was Cronbach α = 0.67 at 18 years of age and Cronbach α = 0.70 at 24 years of age.