Chunk #61 — Methods — Multi-trait conditional GWAS analysis using summary data

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Causal associations between risk factors and common diseases inferred from GWAS summary data.

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environmental or genetic effects that are not correlated with the valid instruments, our estimate of conditional effect does not suffer from the bias described in Aschard et al.23, as confirmed by simulation (Supplementary Fig. 6). We have implemented mtCOJO in the GCTA software package (URLs).