One prediction from the DM is that heavier drinkers should experience greater subjective response on the ascending limb. In those samples testing comparisons (stimulant, sedative, or other) on the ascending limb, however, heavier drinkers reported somewhat lower response, although this effect was not significantly different from 0, g = −0.06 (95% CI: −0.33, 0.22), and varied significantly across studies, Qwithin(11) = 23.13, p = .02, I2 = 52.44. See Table 3. Comparisons on the descending limb resulted in a similar effect, g = −0.08 (95% CI: −0.32, 0.17), although the size of the effect did not vary significantly across studies, Qwithin(8) = 9.02, p = .34, I2 = 1.28.
