1,052 white, non-Hispanic, European ancestry patients with UC extending beyond the rectum and 2,571 white, European ancestry controls were genotyped using Illumina HumanHap300v1, HumanHap300v2, HumanHap550v1 or HumanHap550v3 Genotyping BeadChips (Illumina, Inc., San Diego, CA,) at the Feinstein Institute for Medical Research. Control data were obtained from our CD GWAS2,4 or from studies 64 and 65 deposited in the Illumina iControlDB (http://www.illumina.com/pages.ilmn?ID=231). Informed consent was obtained using protocols approved by each local institutional review board. More details about study subjects and the Illumina Genotyping BeadChips used to genotype groups of study subjects are available in the Supplementary Methods and Supplementary Table 1 online.
