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Chunk #14 — Materials and Methods — Scenario A

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies.
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The method begins by choosing initial guesses for the haplotypes in – by default, we choose haplotypes that are consistent with the observed genotype data but phased at random. We then perform a number of MCMC iterations. Each iteration updates every study individual i (in some arbitrary order) in two steps: