Chunk #4 — Materials & methods — Identification of ancestry-related differences in common & rare variants

Source

Dissecting ancestry genomic background in substance dependence genome-wide association studies.

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To identify the ancestry-related differences in GWAS-relevant genes and their interacting partners, we performed distinct analyses for variants with minor allele frequency (MAF) ≥1% (common variants) and variants with a MAF <1% (rare variants; RVs).