AN cases from the 15 sites were genotyped using Illumina 660W-Quad arrays (Illumina, Inc., San Diego, CA, USA) at the Wellcome Trust Sanger Institute. Funding was available only for genotyping AN cases. Thus, control genotypes were selected from existing datasets matched as closely as possible to the ancestry of cases and Illumina arrays as similar as possible to the 660W array (Table S1). Quality control (QC) of directly typed variants was performed within each of the 15 case-control datasets (Table S2, Supplementary Information).
