order to confirm this finding. Another limitation is the limited power of our replication sample for both AA and EA due to relatively small sample size. In an attempt to address this limitation, we have carried out a combined analysis that shows an association of rs1342043 with CA in AA. We find no association with CA in our EA population, possibly due to the underpowered sample size but also possibly due to limited SNP coverage in the EA population of only 12%. Since the coverage in the AA population is only 42%, further genotyping is warranted to fully characterize the association of common genetic variation in NCS-1 with CA.
