Finally, these data allow comparisons between humans and other animals, with particular relevance for studies of human disease. The current manuscript describes a human-specific pattern for CALB1 in the hippocampus compared to mouse and rhesus monkey. There are certain to be many such differences. In this light, these data should be extremely valuable from a translational perspective, allowing analysis of candidate genes and functional parcellation derived from genetic and imaging studies, and as a baseline for investigating neurological and neuropsychiatric disease.
