Two additional chromosomal regions harbored SNPs with nominal evidence of replication (P≤3.64x10-3): rs13154187 in the Lysine (K)-Specific Demethylase 3B (KDM3B) gene on chromosome 5 and rs16925298 in the Lysine (K)-Specific Demethylase 4C (KDM4C) gene on chromosome 9. Although Major Histocompatibility Complex, Class II, DQ Alpha 1 (HLA-DQA1) SNPs on chromosome 6 also had nominal associations with HIV status in WIHS, opposing directions of association were observed between UHS and WIHS (Table 2). The genome-wide significant finding on chromosome 19 observed in UHS was not replicated in WIHS: rs3987765 replication p = 0.47.
