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Chunk #2 — Introduction

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MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.
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associated with obesity, metabolic syndrome and T2D [16], [17], [18], [19]. The influence of genetic variants on miRNA expression has recently been reported in a study of miRNA expression in human fibroblasts [20], where 12 cis miRNA eQTLs were reported as significant, out of the 121 miRNAs tested (N = 180), motivating us to assess if genetic drivers of miRNA expression will also be present in adipose tissue.