of Hardy-Weinberg equilibrium (39) in controls were already flagged for exclusion. A total of 435,291 SNPs met these criteria and were included in the final analysis dataset (included as a Supplemental File, “mddC.bim”). Additional quality control checks are described in the Supplemental Methods). Thirteen controls were genotyped in a different study using the Illumina 317K platform and, of the 82,636 SNPs common to both platforms, the genotype agreement was 99.94%.
