were not statistically significant (p=0.3 using two-tailed t-test for each comparison), likely due to the small number of observations in each group (n=5 in cases, n=4 in controls). Similarly, neither mean CNV size (220kb versus 150kb) nor mean gene content (1.8 versus 1.2 genes per CNV) was significantly different between cases and controls when all (de novo and transmitted) rare CNVs were considered together (p=0.3 using two-tailed t-test for each comparison).
