Note also that in the microsatellite screens, the two-point analysis in many instances found higher LOD scores than the multipoint analysis. For example, the two-point analysis found weak evidence on chromosome 7 with a LOD score over 1 at 116.6 cM (in the vicinity of the SNP linkage signals), while multipoint LOD scores did not reach 1 on chromosome 7 (the maximum LOD was 0.89 at 140 cM).
