GHB, a short chain fatty acid and a GABA derivative, has been characterized as an inhibitory neurotransmitter in the brain and neuromodulator of the dopaminergic, opioid and GABA-ergic neurotransmitter systems [7, 8]. While approved by the US FDA for the treatment of narcolepsy, the abuse of GHB as a psychotropic drug became a world-wide problem by the late 90’s. Known to recreational users as G, gib, soap, salty water or nitro, exposure to GHB induces short term amnesia, increases libido and euphoria. The disinhibition of sexual behavior produced by GHB has also given it the moniker of a date-rape drug because of its abuse in sexual assaults.
