Next, we examined whether the associations between GR (AUD-GR and EXT-GR) and drinking outcomes were moderated by sex of the co-twin. The results indicated that among opposite-sex twins the relationships between GR (AUD-GR and EXT-GR) and frequency of intoxication at ages 14 and 17 were significantly moderated by co-twin sex (Table 4). Specifically, the association between GR and intoxication frequency was greater amongst females with male co-twins. These effects were not observed at age 12 or 22.
